BergacynFF®

Bergacyn®FF is a patented, clinically-studied, chemically solvent-free Bergamot citrus and Cynara leaf extract blend. It promotes liver and cardiometabolic health and supports healthy weight management by protecting against adipose (fat) tissue dysfunction. BergacynFF’s polyphenol, sesquiterpene, and citrus pectin bioactives synergistically combine to deliver enhanced bioavailability of multiple plant actives. Poor eating and lifestyle habits, aging, and significant hormonal shifts, like menopause, challenge proper blood sugar control and insulin output. These changes overwhelm/remodel the body’s normal storage of fats, regulation of cytokines, and balance of oxidative stress – particularly in the liver. Ultimately, healthy fat transport is disturbed and the vascular system, liver, and abdominally centered tissue become reserve sites for the deposit of inflammatory fats. Mildly increased uric acid (UA) levels appear to mediate early-stage fat accumulation in the liver. Among Bergacyn’s multitargeted actions, it’s support of balanced UA levels in modulating lipid metabolism in the liver is trendsetting. Clinical studies include:- Lipid Metabolism – Healthy/Metabolic Syn. (600mg/12 wk; DBRC; n=102) • Supports healthy liver function • Supports healthy weight management • Reduces liver congestion • Promotes healthy uric acid levels Metabolic Health – DM, Type 2 (600 mg/16 wk.; DBRC; n=80) • Protects liver cells from oxidative stress • Protects liver cells from inflammation Weight Management – Obesogenic mice (100 mg/kg ~ 600 mg HED/d; Control; n=24) • ↑Brown:white fat ratio (promotes thermogenesis) • ↓Total and LDL cholesterol • ↑PPARγ and ↓NFκB Bioavailability/Synergism • 1.5X > standalone extracts